Three new features added to SimpleMine

WormBase SimpleMine users can now batch-download chromosome coordinates and transcription factors within 2kb of promoter regions. When searching for interacting genes, there is a new option to exclude high-throughput interaction results.

We have also developed an instance of SimpleMine for the Alliance of Genome Resources for researchers to batch download essential gene information for worm, yeast, fly, Xenopus, zebrafish, mouse, rat, and human. Your feedback on our work is always appreciated! Please email help@wormbase.org.

New Author First Pass release marks the transition to ACKnowledge!

WormBase is excited to announce that the Author First Pass project received support from the National Library of Medicine and is now officially known as ACKnowledge (Author Curation to Knowledgebase). This change reflects our commitment to expanding artificial intelligence (AI)-enhanced community curation to capture more detailed experimental findings and to introduce our curation pipeline to additional model organism communities and their respective knowledgebases.

While busy transitioning our project and enhancing our AI methods, we also implemented further improvements to the current pipeline based on continuing valuable feedback from authors.  These improvements will help authors add more information about their papers and readily find previously published papers processed by our pipeline for curation using our Author Curation Portal.

A full list of enhancements is available in the V4 Release Notes.

We could have not achieved this exciting milestone without the continuous support and participation of the wonderful C. elegans community. Please continue to contribute to this important initiative!

WS286 genome browser

The new genome browser software is a live, in-page genome browser that you can add tracks to, pan, zoom and do a variety of things JBrowse 1 could do without leaving the page. If you’d like a full page JBrowse 2, you can click on the link just above the genome browser, or if you’d like to use JBrowse 1, you can click on the “Legacy” link just below JBrowse 2 to get the old JBrowse 1 image and link back. Please let us know if you have any comments or questions by writing to help@wormbase.org.

Analysis refresh of Brugia malayi

WormBase build WS285 contains an analysis refresh of the Brugia malayi genome, so – expect, for example, new and better homologs and expression data. Did you know that WormBase contains 9 species in addition to C. elegans? All of these species have unique manually curated data and gene models. 

Strain data update from CGC

WormBase regularly gets data from leading stock centers such as the Caenorhabditis Genetics Center (CGC)   and National Bioresource Project (NBRP) . Release WS285 contains an extra-large update, with more than 1,500 new strains imported from the CGC. Perhaps there is one that is the perfect study object for you?