C.elegans motion assay adapted for use in anthelminth studies

A paper called Utilization of computer processed high definition video imaging for measuring motility of microscopic nematode stages on a quantitative scale: “The Worminator” was published by Bob Storey et al in the International Journal for Parasitology.

It describes a modification of the WormAssay software, a tool for motility studies in C.elegans.

These additions allow the analysis of the motility in microscopic lifestages, as found in parasitic nematodes, enabling new ways in automating anthelminth screens.

Anthelmintic drug chapter updated in WormBook

Dear WormBook reader,

Anthelmintic drugs and nematicides: studies in Caenorhabditis elegans, by Lindy Holden-Dye and Robert Walker, has been added to the Disease models and drug discovery section. This chapter updates the 2007 chapter, Anthelmintic drugs, also by Holden-Dye and Walker. This chapter discusses the use of C. elegans as a model ‘parasite’, and reviews its use in the study of nematode control and as a platform for anthelmintic and nematicide discovery and development.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook.

Jane