Focus on Parasite Papers

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For the upcoming WS246 release, a set of new papers have been added to the WormBase database. Some papers of interest to the parasite community are shown below.

Coles GC, Bauer C, Borgsteede FH, Geerts S, Klei TR, Taylor MA, Waller PJ. World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet Parasitol. 1992 Sep;44(1-2):35-44.

linked genes: Bma-pdi-2
ParaSite: Bma-pdi-2

Wiśniewski M, Lapiński M, Zdziarska A, Długosz E, Bąska P. Molecular cloning and analysis of Ancylostoma ceylanicum glutamate-cysteine ligase. Mol Biochem Parasitol. 2014 Aug;196(1):12-20.

linked genes: Bma-gcs-1 Acey_s0084.g1747
ParaSite: (there are two alternative assemblies on ParaSite for A.ceylanicum) Acey_s0084.g1747 ANCCEY_09480 Bma-gcs-1

Jawaharlal JP, Madhumathi J, Prince RP, Kaliraj P. Repeat region of Brugia malayi sheath protein (Shp-1) carries Dominant B epitopes recognized in filarial endemic population. Acta Parasitol. 2014 Sep;59(3):454-8.

linked genes: Bma-shp-1
ParaSite: Bma-shp-1

WormBook chapter on Epithelial Junctions, cytoskeleton, and polarity updated

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Dear WormBook reader,

Epithelial junctions, cytoskeleton, and polarity, by Gabriella Pásti and Michel Labouesse, has just been added to the Cell biology section of WormBook. This chapter updates Epithelial junctions and attachments, by Michel Labouesse, originally published in 2006. Focusing on cellular aspects of epithelial cells, the chapter describes basic features of C. elegans apical junctions, establishment and maintenance of epithelial polarity, the epithelial cytoskeleton, and hemidesmosome-like cell-extracellular matrix junctions.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook.

Jane

WormBook chapter on gene structures in C.elegans updated

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Dear WormBook reader,

Overview of gene structure in C. elegans, by John Spieth, Daniel Lawson, Paul Davis, Gary Williams, and Kevin Howe, has just been added to the Genetics and genomics and Molecular biology sections of WormBook. This chapter updates Overview of gene structure, by John Spieth and Daniel Lawson, originally published in 2005. The updated chapter describes some of the ways in which gene structures are currently curated in WormBase, primarily focusing on transcribed regions of genes, and also includes an updated description of non-coding RNA genes.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook.

Jane

new Worm Breeder's Gazette out

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Dear Worm Researcher,

Volume 20, Number 2 of The Worm Breeder’s Gazette has been published. This issue highlights genome editing and includes 4 articles describing improvements in CRISPR/Cas9 technology, web resources useful for those experiments, and links to published papers in the field. The issue also includes descriptions of other useful tools for the worm community, a caution about the potential effects of bacto-peptone on worm behavior, and several other research summaries. There are also worm humor articles, worm art, and new lab announcements.

Please proceed to http://www.wormbook.org/wbg/ to view the latest issue of the Gazette.

Best regards,

Jane Mendel
Editor, WormBook

WormBook chapter on Q neuroblast migration published

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Dear WormBook reader,

Development and migration of the C. elegans Q neuroblasts and their descendants by Teije Middelkoop and Rik Korswagen has been added to the Developmental control section of WormBook. This chapter describes the complex mechanisms that control the establishment of the left/right asymmetry in the Q neuroblasts and the migration of their descendants.

Please proceed to read this chapter and others on nematode biology at www.wormbook.org. If you have any comments or suggestions, please submit them via the Feedback page.

Thank you for your interest in WormBook.

Jane