New release of the Alliance of Genome Resources

Check out the latest release (5.1.0) of the Alliance of Genome Resources for your favorite worm gene and get great comparative data across the major model organisms. A notable addition to this Alliance release are the member pages which link to organism or GO related data within the Alliance and to the model organism database or the GO Consortium. These pages can be accessed from the “Members” menu at the top of Alliance web pages. See the complete release notes for the 5.1.0 release.

WormBase release WS282

New release of Wormbase WS282 is out. Details related to the data and changes in WS282 are available in the release notes.

A highlight of this release is that variant data are now also available in VCF file format:

c_elegans.PRJNA13758.WS282.variations.vcf.gz and c_briggsae.PRJNA10731.WS282.variations.vcf.gz

These files are available in the respective “species” folder on the WormBase FTP site.

Change to disease statements in gene descriptions for WS279

Due to non-stringent human ortholog(s) and their associated diseases, C. elegans gene descriptions (displayed in the “Overview widget” of gene pages) often had spurious diseases associated with their human orthologs. With WS279, we imposed a stringency filter and only those disease associations to ortholog(s) called by more than one orthology prediction method are included in the gene description. This change has improved the accuracy of statements that read “human orthologs of this gene are implicated in <disease(s)>”. However, please note that this change has also resulted in the loss of such statements for several hundred gene descriptions due to the increased stringency.