Due to non-stringent human ortholog(s) and their associated diseases, C. elegans gene descriptions (displayed in the “Overview widget” of gene pages) often had spurious diseases associated with their human orthologs. With WS279, we imposed a stringency filter and only those disease associations to ortholog(s) called by more than one orthology prediction method are included in the gene description. This change has improved the accuracy of statements that read “human orthologs of this gene are implicated in <disease(s)>”. However, please note that this change has also resulted in the loss of such statements for several hundred gene descriptions due to the increased stringency.
A new release of WormBase, WS276 is live on the website. Please see the release notes which contain complete information about this release.
Data changes: note that C. elegans gene descriptions in the “Overview” section of gene pages have improved orthology statements to human genes. WormBase uses the DIOPT orthology data from the Alliance of Genome Resources and has increased stringency by displaying only those human orthologs that have been determined by three or more methods. This should significantly improve the orthology data in WormBase which is also reflected in the gene descriptions.
Known Issues: the circRNAs failed mapping so sequence and genomic position are not available for this release, but will be in the WS277 release.
WormBase is happy to announce that the microPublication Biology journal is now fully listed in PubMed!
To make articles easier to cite and discover, every microPublication now receives a PubMed ID, a PubMed Central ID, and a DOI. If you have published with us in the past, consider updating your citations. Indexing is retroactive for all past articles.
You can see microPublications in PubMed by browsing the full index at
PubMed Central. Or look for microPublications during normal searches at PubMed or PubMed Central.
We look forward to receiving more submissions!