Analysis refresh of Brugia malayi

WormBase build WS285 contains an analysis refresh of the Brugia malayi genome, so – expect, for example, new and better homologs and expression data. Did you know that WormBase contains 9 species in addition to C. elegans? All of these species have unique manually curated data and gene models. 

Strain data update from CGC

WormBase regularly gets data from leading stock centers such as the Caenorhabditis Genetics Center (CGC)   and National Bioresource Project (NBRP) . Release WS285 contains an extra-large update, with more than 1,500 new strains imported from the CGC. Perhaps there is one that is the perfect study object for you? 

WormBase Parasite launches new release

WormBase ParaSite launches its new release 17 with an exciting list of new/updated genomes and new features:

  • Integration of AlphaFold 3D protein structures for 8 species.
  • Addition of 11 new genome assemblies of which 6 are new species.
  • Annotation updates for 2 genomes.
  • Gene-phenotype associations are now available in our FTP directory.
  • Improvements in the way external gene synonyms are integrated and displayed.
  • Deployment of WebApollo instances for more species to further facilitate community curation.

For more information please see the WormBase ParaSite blog.

For miRNA fans

For miRNA fanatics out there, we have added 90 miRNA gene clusters from MirGeneDB to the C. elegans annotation in release WS284. This complements the 20 clusters (800 objects) which were already there, making the WormBase miRNA collection possibly the most complete in the world. You can access the miRNAs through the web pages https://wormbase.org/search/all/miRNA, or through JBrowse tracks “Curated Genes(noncoding)” e. g. And don’t forget WormBase also has an impressive collection of other non-coding RNAs as well; circRNAs, lincRNAs, piRNAs, snRNA, snoRNAs, precursors and many more. Happy investigating!

New release of the Alliance of Genome Resources

Check out the latest release (5.1.0) of the Alliance of Genome Resources for your favorite worm gene and get great comparative data across the major model organisms. A notable addition to this Alliance release are the member pages which link to organism or GO related data within the Alliance and to the model organism database or the GO Consortium. These pages can be accessed from the “Members” menu at the top of Alliance web pages. See the complete release notes for the 5.1.0 release.