WormBook chapter on gene structures in C.elegans updated

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Dear WormBook reader,

Overview of gene structure in C. elegans, by John Spieth, Daniel Lawson, Paul Davis, Gary Williams, and Kevin Howe, has just been added to the Genetics and genomics and Molecular biology sections of WormBook. This chapter updates Overview of gene structure, by John Spieth and Daniel Lawson, originally published in 2005. The updated chapter describes some of the ways in which gene structures are currently curated in WormBase, primarily focusing on transcribed regions of genes, and also includes an updated description of non-coding RNA genes.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook.

Jane

new Worm Breeder's Gazette out

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Dear Worm Researcher,

Volume 20, Number 2 of The Worm Breeder’s Gazette has been published. This issue highlights genome editing and includes 4 articles describing improvements in CRISPR/Cas9 technology, web resources useful for those experiments, and links to published papers in the field. The issue also includes descriptions of other useful tools for the worm community, a caution about the potential effects of bacto-peptone on worm behavior, and several other research summaries. There are also worm humor articles, worm art, and new lab announcements.

Please proceed to http://www.wormbook.org/wbg/ to view the latest issue of the Gazette.

Best regards,

Jane Mendel
Editor, WormBook

WormBook chapter on Q neuroblast migration published

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Dear WormBook reader,

Development and migration of the C. elegans Q neuroblasts and their descendants by Teije Middelkoop and Rik Korswagen has been added to the Developmental control section of WormBook. This chapter describes the complex mechanisms that control the establishment of the left/right asymmetry in the Q neuroblasts and the migration of their descendants.

Please proceed to read this chapter and others on nematode biology at www.wormbook.org. If you have any comments or suggestions, please submit them via the Feedback page.

Thank you for your interest in WormBook.

Jane

Mechanosensation methods updated in WormBook

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Dear Worm Researchers,

Assaying mechanosensation, by Marty Chalfie, Anne Hart, Cathy Rankin, and Miriam Goodman, has been published in the Behavioral assays section of WormMethods. This chapter updates and expands the mechanosensation assays currently found in the 2006 chapter, Behavior, edited by Anne Hart. In addition to updating assays for gentle and harsh touch, precipice response, nictation, head withdrawal and foraging, tap reflex, habituation to tap, and nose touch, the new chapter describes mechanical stimulation during electrical or optical recording.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook,

Jane Mendel
Editor, WormBook

Worm Breeders Gazette submission deadline

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Dear Worm Researchers,

The deadline for submissions to the next issue of The Worm Breeder’s Gazette is Monday, September 15, with publication following about a week later. While we will accept all articles, we would like to emphasize CRISPR methodology in this issue. So, if you have developed or improved any techniques you think would be useful to the community, please take the time to write up your protocol and submit it at http://www.wormbook.org/wbg/.

In addition to articles summarizing research, we also welcome announcements (particularly for new labs), editorials, humor, and artwork.

Articles should be a single page in length.

Looking forward to your contributions to the Gazette,

Jane

Jane Mendel
Editor, WormBook