Focus on Parasite Papers

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For the upcoming WS246 release, a set of new papers have been added to the WormBase database. Some papers of interest to the parasite community are shown below.

Yadav S, Gupta S, Selvaraj C, Doharey PK, Verma A, Singh SK, Saxena JK. In silico and in vitro studies on the protein-protein interactions between Brugia malayi immunomodulatory protein calreticulin and human C1q. PLoS One. 2014 Sep 3;9(9):e106413.

linked genes: Bm6412
ParaSite: Bma6412

Galvin BD, Li Z, Villemaine E, Poole CB, Chapman MS, Pollastri MP, Wyatt PG, Carlow CK. A target repurposing approach identifies N-myristoyltransferase as a new candidate drug target in filarial nematodes. PLoS Negl Trop Dis. 2014 Sep 4;8(9):e3145.

linked genes: Bma-nmt-1 , nmt-1
ParaSite: Bma-nmt-1

Terry FE, Moise L, Martin RF, Torres M, Pilotte N, Williams SA, De Groot AS. Time for T? Immunoinformatics addresses vaccine design for neglected tropical and emerging infectious diseases. Expert Rev Vaccines. 2014 Sep 5:1-15.

linked genes: Bma-prdx-2
ParaSite: Bma-prdx-2

WormBook: DNA repair chapter updated

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Dear WormBook reader,

Replication and repair by Ann Rose has just been added to the Molecular biology section of WormBook. This chapter updates and greatly expands the 2006 chapter DNA repair by Nigel O’Neil and Ann Rose. Over the past few years there has been an explosion of research using C. elegans to study many aspects of DNA repair and the updated chapter points to several recently published reviews. The new chapter summarizes those reviews and highlights the use of C. elegans in the study of the Fanconi Anemia (FA) repair pathway.

Please proceed to read this chapter and others on nematode biology at http://www.wormbook.org/. If you have any comments or suggestions, please submit them via the Feedback page on wormbook.org.

Thank you for your interest in WormBook.

Jane

Focus on Parasite Papers

by Leave a Comment

For the upcoming WS246 release, a set of new papers have been added to the WormBase database. Some papers of interest to the parasite community are shown below.

Coles GC, Bauer C, Borgsteede FH, Geerts S, Klei TR, Taylor MA, Waller PJ. World Association for the Advancement of Veterinary Parasitology (W.A.A.V.P.) methods for the detection of anthelmintic resistance in nematodes of veterinary importance. Vet Parasitol. 1992 Sep;44(1-2):35-44.

linked genes: Bma-pdi-2
ParaSite: Bma-pdi-2

Wiśniewski M, Lapiński M, Zdziarska A, Długosz E, Bąska P. Molecular cloning and analysis of Ancylostoma ceylanicum glutamate-cysteine ligase. Mol Biochem Parasitol. 2014 Aug;196(1):12-20.

linked genes: Bma-gcs-1 Acey_s0084.g1747
ParaSite: (there are two alternative assemblies on ParaSite for A.ceylanicum) Acey_s0084.g1747 ANCCEY_09480 Bma-gcs-1

Jawaharlal JP, Madhumathi J, Prince RP, Kaliraj P. Repeat region of Brugia malayi sheath protein (Shp-1) carries Dominant B epitopes recognized in filarial endemic population. Acta Parasitol. 2014 Sep;59(3):454-8.

linked genes: Bma-shp-1
ParaSite: Bma-shp-1

2015 SRF Summer Scholars Program

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Paid Summer Research Opportunity for Undergraduates

The SRF Summer Scholars Program offers undergraduate students the opportunity to conduct biomedical research to combat diseases of aging. One such opportunity in the laboratory of Dr. Gordon Lithgow at the Buck Institute for Research on Aging will investigate the importance of metal homeostasis in C. elegans, which has been associated with lifespan, healthspan, and a number of age-related human diseases, such as Alzheimer’s, Parkinson’s Disease, and ALS.

The Summer Scholars Program not only offers students the opportunity to conduct their own research project but also the chance to develop communication skills. Students participating in the program will hone their writing skills via periodic reports, which are designed to emulate text scientists commonly must produce. Additionally, a poster presentation at a SRF-sponsored conference at the end of the summer will provide the Summer Scholars with an opportunity to present their results to scientists from other research institutions.

To learn more about this summer internship program and other paid research opportunities at such institutions as the Harvard Stem Cell Institute, the Sanford-Burnham Medical Research Institute, and the Scripps Research Institute, at www.sens.org/2015-summer-scholars.

Online applications will be accepted until 12 pm PST February 2, 2015. If you have any questions about the program, please feel free to contact the SRF Director of Education Greg Chin

2015 SRF Summer Scholars Flyer

2015 SRF Summer Scholars Flyer