New version of Worm Breeder’s Gazette!

Dear Worm Breeders —

We are pleased to announce the next iteration of the Worm Breeder’s Gazette with some exciting new changes.

Starting today, the Gazette will publish articles on a rolling basis with only a brief editorial period to review formatting. We’ve also made the submission process simpler and more robust. For example, you can start a submission online, saving your progress at any time to complete later.

By accelerating the availability of Gazette articles, we seek to preserve the original spirit of the Gazette: publication of breaking results and new methods of general interest to the community in a brief and digestible format. Submissions will still be restricted to approximately one printed page with notable exceptions for the inclusion of rich media such as images and movies.

We look forward to your contributions!
— The Worm Breeder’s Gazette Editors, Jane Mendel and Todd Harris.

To participate in the new version of the Gazette, first register for an account.

Once registered, you will be able to submit an article online.

If you’ve participated in the past, you will need to reset your password first.

Subscribe by email and follow us on Twitter!

May 2016: 8 new labs joining the community

8 new labs have registered with WormBase and the CGC. Please join us in welcoming these labs to the community!

Alex Mendenhall ARM wam University of Washington, Seattle, WA
Hiroaki Miki CRB dcr Osaka University, Osaka, Japan website
Megan Hwa Brewer MHB nna Sydney Medical School, Concord, NSW, Australia
Suhong Xu SHX zju Zhejiang University, Hangzhou, Zhejiang, China website
Tamara Mikeladze-Dvali TMD mik Biozentrum der LMU Mnchen, Planegg-Martinsried, Germany website
Matt Crook TWP mxc Whitman College, Walla Walla, WA
Anna K Allen WDC ana Howard University, Washington, DC website
Wolfgang Fischle WFK cbd Max Planck Institute for Biophysical Chemistry, Goettingen, Germany website

Nichol Thomson passes away

Nichol Thomson, one of the founding figures of C. elegans research, recently passed away, peacefully, at the age of 91, on 26th March 2016.   He was responsible for a major part of  all the early electron microscopy work on the worm, and indeed his initial results with fixing  and sectioning C. elegans samples were decisive in persuading Sydney Brenner to work on C. elegans rather than some other nematode.   Nichol was an important influence, inspiration, colleague and friend to all of the C. elegans researchers at MRC-LMB in Cambridge UK, from 1964 until his retirement in 1989.

Check out the first chapter of WormBook in GENETICS!

The first chapter of WormBook in GENETICS, CRISPR-Based Methods for Caenorhabditis elegans Genome Engineering, by Daniel J. Dickinson and Bob Goldstein, is now available!

The advent of genome editing techniques based on the clustered regularly interspersed short palindromic repeats (CRISPR)–Cas9 system has revolutionized research in the biological sciences. CRISPR is quickly becoming an indispensible experimental tool for researchers using genetic model organisms, including the nematode Caenorhabditis elegans. Here, we provide an overview of CRISPR-based strategies for genome editing in C. elegans. We focus on practical considerations for successful genome editing, including a discussion of which strategies are best suited to producing different kinds of targeted genome modifications.