There is a growing body of literature showing that C. elegans is a great model that contributes to the study of human disease. Recently Dr. Andy Golden alerted us to this bit of news: Check out the show ‘Diagnosis’ on Netflix by the New York Times (episode 4). There is a very rare disease caused by mutations in the human KCNMA1 gene. If you study slo-1, perhaps you can help these patients.
Check out this useful chapter ‘The Caenorhabditis elegans Transgenic Toolbox‘ by Jeremy Nance and Christian Frøkjær-Jensen in the latest issue of WormBook, GENETICS.
Talks delivered at the WormBase workshop as part of the International C. elegans meeting at UCLA in June 2019 are now available on Youtube. Please note that these are recordings done at the workshop with external cameras and microphones, so apologies if they are not of the highest quality. They are linked from their titles below–
- Introduction to the WormBase webpages and widgets
- WormBase data mining tools: SimpleMine, WormMine, BioMart
- WormBase ontologies and gene set enrichment analysis
- WormBase JBrowse: tutorial and demo
- Community curation
- Introduction to the Alliance of Genome Resources
If you have started a new worm lab or are looking for nomenclature guidelines for genes, alleles and other genetic entities, please consult this page of our online user guide–https://wormbase.org/about/userguide/nomenclature#f1il048b3g6e2597cmdjkh–10
Different types of properly named entities (genes, alleles, strains, trangenes, etc.) in published papers are identified by text-mining and other WormBase tools and/or via manual curation. Following official nomenclature guidelines makes your data discoverable by WormBase and thus to the whole community!