New methods for genome engineering (TALENs, CRISPR-Cas9, etc.) are increasingly being applied to C. elegans. Please remember to use nomenclature guidelines when naming these engineered alleles or constructs. Refer to the guidelines in the ‘Genome Engineering’ widget here.
A situation which is not covered here (and which I have yet to see a definitive agreement) is how to name natural variants which are reverted to the reference using CRISPR or other methods. For example, if I take a CB4856 SNP variant (C) , WBVar…etc, and cleanly convert it to the N2 reference sequence (G), should this allele receive a new designation?
Some possibilities (to adhere closely to the wiki example) would be to use
bus-50(e5000[WBvar…>G]) using the variant designation or
bus-50(e5000[X:2992500, N2>CB4856]) to use a congenic-like designation or
qqR1[X:2992500, N2>CB4856] for a stricter introgression designation for the allele. The first two of these seem lengthy so I wonder if anyone has come to a consensus on this type of thing.