If you’d like to read about the latest developments at WormBase—literature curation efforts, features about the web interface, data mining options for users, and how WormBase as a founding member, interacts with the Alliance of Genome Resources to aid in cross-species data comparisons, check out our paper in Nucleic Acids Research.
Paper of Interest: Identification of functional long non-coding RNAs in C. elegans.
This paper predicts 143 new multi-exonic lncRNA loci in C. elegans, along with ~3,000 possible new single-exon lncRNA loci.
Paper of Interest: OrthoList 2
The new comparative genomic analysis between C. elegans and humans, OrthoList 2 (OL2), was just published early online in GENETICS. OL2 comes with a new web-based tool that allows for rapid searches of OL2 by worm or human gene identifiers, protein domains (InterPro and SMART), or human-disease associations (OMIM), and also includes updated RNAi resources. The paper describes OL2 and various findings, including how the content of OL2 compares with the original OrthoList tool. The web-based tool for accessing OL2 is here.
Please specify allele and strain names in publications
WormBase curates data from published papers and attaches different types of data such as phenotype, overview, expression, human disease model, etc., to genetic entities such as genes, alleles, strains or transgenes. These are also bonafide ‘objects’ in our database which allow us to attach data to them. If we cannot find these named genetic entities in your paper it becomes extremely difficult for us to curate the paper. It is not enough to just specify the amino acid or nucleic acid change of a mutation, we need either the strain or allele name to curate the paper.
Latest chapter in WormBook about cell movement
Check out the latest chapter of WormBook in Genetics-‘Invading, Leading and Navigating Cells in Caenorhabditis elegans: Insights into Cell Movement in Vivo‘, by David R. Sherwood and Julie Plastino.