WormBase seeks a Biological Curator

WormBase at Caltech (at Pasadena, CA, USA) currently has seven full-time biological curators as well as several bioinformaticians and software developers. The Caltech group annotates gene expression patterns, gene regulation, functional descriptions, phenotypes, microarray data, cell functions, and protein and gene interactions.  We continually try to obtain, store and display whatever information has become most relevant to our community.

We are seeking an individual with substantial C. elegans experience to help analyze gene functions and interactions and incorporate them into WormBase.  Curation places a premium on broad scientific knowledge, excellent communication skills, and creative intelligence, as well as on patience and hard work.  Computer literacy in UNIX or Linux and in Perl is a plus, but is not required, since curators have the opportunity to develop their skills in bioinformatics at Caltech.  While demanding high skill and willingness to serve others, biological curation at Caltech also offers rewards beyond that of a postdoc, one of which is a wide range of future job prospects: biologists who become curators can remain at the forefront of research, and also have the option to move to bioinformatics. A curator’s salary is higher than most postdoc’s, and the general quality of life in Pasadena and Caltech is good. Curators at Caltech work in an excellent academic environment, where they can interact with several laboratories carrying out genomics both at Caltech itself and at affiliated institutions.

Please contact Paul Sternberg (pws@caltech.edu) for more information.

Publication Spotlight: A phylogeny and molecular barcodes for Caenorhabditis, with numerous new species from rotting fruit

I would like to draw your attention to f Karin Kiontke et al.’s new paper in BMC Evolutionary Biology  on the phylogeny and molecular barcodes for Caenorhabditis. The authors describe quite a few new strains and species, which should be of interest to anyone interested in phylogeny of nematodes.

But they couldn’t find any sister species to C.elegans, so that challenge is still on.

Ascaris suum genome in WormBase

The newly published Ascaris suum genome (Aaron Jex, et al, Nature 2011 Oct 2) is available at WormBase including it’s geneset. The data has been added to GBrowse/BLAT/BLAST and can be downloaded as FASTA/GFF3 files from the WormBase FTP server.

Ascaris suum is a model for other parasitic Ascaris, as well as causing itself economic damage to pig farming. In addition it is known to be resistant to a large number of antihelminth chemicals.