WS247: Parasite Papers I

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For the upcoming WS247 release, a set of new papers have been added to the WormBase database. Some papers of interest to the parasite community are shown below.

Rodrigo WW, Dassanayake RS, Weerasena SJ, Silva Gunawardene YI. Novel parasitic nematode-specific protein of bovine filarial parasite Setaria digitata displays conserved gene structure and ubiquitous expression. Trop Biomed. 2014 Sep;31(3):514-24.

genes referred to: Bm8739

Tiwari S, Wadhawan M, Singh N, Rathaur S. Effect of CDNB on filarial thioredoxin reductase : A proteomic and biochemical approach. J Proteomics. 2015 Jan 15;113:435-46.

genes referred to: ced-3 , ced-9 , Bma-trxr-1 , Bma-ced-3 , Bm14668

Kulke D, von Samson-Himmelstjerna G, Miltsch SM, Wolstenholme AJ, Jex AR, Gasser RB, Ballesteros C, Geary TG, Keiser J, Townson S, Harder A, Kruecken J Characterization of the Ca2+-gated and voltage-dependent K+-channel Slo-1 of nematodes and its interaction with emodepside. PLoS Negl Trop Dis. 2014 Dec 18;8(12):e3401.

genes referred to: sle-1 , slo-1 , Bma-slo-1 , Ovo-slo-1

Lustigman S, Melnikow E, Anand SB, Contreras A, Nandi V, Liu J, Bell A, Unnasch TR, Rogers MB, Ghedin E. Potential involvement of Brugia malayi cysteine proteases in the maintenance of the endosymbiotic relationship with Wolbachia. Int J Parasitol Drugs Drug Resist. 2014 Aug 26;4(3):267-77.

genes referred to: Bm1665 , Bma-cpl-6 , Bma-cpl-2 , Bma-cpl-7 , Bma-cpl-8 , Bma-cpl-4 , Bma-cpl-5 , Bma-cpl-1

WormBase ParaSite release 2: more genomes and new data-mining tool

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We are pleased to announce the second release of WormBase ParaSite, the home for parasitic worm draft genomes and genomic data in WormBase.

This release includes eight new annotated genomes, taking the total number of nematode and flatworm genomes in WormBase ParaSite to 97, representing 89 species. The new genomes include:

* Fasciola hepatica (PRJEB6687)
* Opisthorchis viverrini (PRJNA222628)
* Pristionchus exspectatus (PRJEB6009)
* Five Steinernema genomes, including Steinernema carpocapsae (PRJNA202318)

    This release also includes a new data-mining tool, the WormBase ParaSite BioMart. The interface and underlying software for this are based on the Ensembl BioMart, the main difference being that WormBase ParaSite BioMart collects data for all species into a single underlying database. This means that a single query can be used to filter and report data from multiple species at once, for example all species of a given taxonomic clade.

    'Mind of a Worm' paper one of the most significant papers!

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    The ‘Mind of a Worm’ paper was chosen as one of 18 most significant biological papers published by the Philosophical Transactions of the Royal Society over its 350 year history.  See the commentary written by Dr. Scott Emmons, additionally all the life sciences papers as well as the physical sciences articles in this issue can be accessed!