Panagrellus redivivus, a free-living nematode often used to study evolution of developmental and behavioural processes in C.elegans has been added to the WS240 release of WormBase.
While its main importance for WormBase is for evolutionary conservation of pathways,P.redivivus is also used as easy to breed microworm feed in aquaculture.
We would like to thank Marissa Macchietto for providing us the data which is also available at the INSDC and as published in Genetics.
As of WS236, published and unpublished allele phenotypes from the books, C. elegans I and II, will be available through gene and allele pages displayed in the phenotype widget. This focused effort added 4,819 phenotype annotations to 1,431 genes. Until now, these data had been hidden in legacy information from C. elegans I and II, and were available in WormBase as a block of text under the concise description in the overview widget of the gene page. As these descriptions constitute valuable gene function information, we are pleased to have these data available for query and computational analysis.
Interested in seeing the expression profile of your favorite gene during development? When you are on the gene page of interest, select the expression widget to open it, and click on the object whose description begins with ‘Developmental gene expression time-course’. On the graph page, clicking on the graphs will result in larger images. We have recently incorporated graphs for over 19,000 genes from the study published in Developmental Cell (Levin et al., 2012). Check out tbx-34 as an example.
This release (WS235) includes the genome of the “eye worm” Loa loa, one of the causative agents of filariasis.
Genome assembly and annotation were performed by the Filarial worms Sequencing Project of the Broad Institute of Harvard and MIT (http://www.broadinstitute.org/).
The C.elegans RNAi library has been extended with 3507 new supplementary bacterial clones and now targets around 87% of currently annotated C.elegans genes. Purchase the complete set of all clones or individual chromosome sets (I, II, III, IV, V and X) which include the pre-existing and new supplemental strains. The complete supplementary sets of RNAi clones and individual chromosome suplementary sets (I, II, III, IV, V and X) are also available to order for those who have previously purchased the pre-existing library.