Coming orthology data changes in WormBase WS276

Many of you have written to us in the past and pointed out some spurious human orthology calls for elegans genes, most of these have been noticed in the gene descriptions that appear in the Overview widget on the gene page. WormBase now uses the DIOPT orthology data from the Alliance of Genome Resources and has increased stringency by displaying only those human orthologs that have been determined by three or more methods. This should significantly improve the orthology data in WormBase which is reflected in the gene descriptions. Note that this change will go live in the WS276 version of WormBase coming soon (late April, 2020).

Alliance of Genome Resources updated

The Alliance (alliancegenome.org) 3.0 version released yesterday, has new features and new data related to the use of model organisms in understanding the genetic and genomic basis of human biology, health and disease. Salient features of the 3.0 release include new allele pages with variant and transcript data, new disease models on gene and disease pages, data files available for download, etc. To learn more about the latest features and data, check out the release notes.