The new comparative genomic analysis between C. elegans and humans, OrthoList 2 (OL2), was just published early online in GENETICS. OL2 comes with a new web-based tool that allows for rapid searches of OL2 by worm or human gene identifiers, protein domains (InterPro and SMART), or human-disease associations (OMIM), and also includes updated RNAi resources. The paper describes OL2 and various findings, including how the content of OL2 compares with the original OrthoList tool. The web-based tool for accessing OL2 is here.
Check out the latest chapter on microRNAs in WormBook
Check out the latest chapter in WormBook, GENETICS: Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs by Victor Ambros and Gary Ruvkun.
High throughput datasets in SPELL now searchable based on topic
Data sets coming from high throughput experiments which reside in SPELL have now been updated with topics so that you can actually search by your favorite topic. You can see the topic search options by clicking the button ‘Options for Filtering Results by Dataset Tags‘ on the SPELL home page under the search box for Gene Name(s).
Which WB tool to use -check out our updated list and links
If you’re wondering which WormBase tool to use for your data needs, check out this updated list of tools with short descriptions for what to use them for. Click on the tool names to be taken directly to the tool.
Check out the Eukaryotic Genomic Databases book!
The Eukaryotic Genomic Databases book has just been released by Springer (Editors: Kollmar, Martin) and contains detailed chapters related to the eukaryotic databases such as WormBase, FlyBase, the yeast databases, SGD and PomBase, etc. The chapters describe database contents and classic use-cases, which assist in accessing eukaryotic genomic data and encouraging comparative genomic research.